Specificity and plasticity of retinotectal connections: a computational model
نویسندگان
چکیده
منابع مشابه
Specificity and plasticity of retinotectal connections: a computational model.
A computational model is presented which simulates the development and regeneration of orderly connections between retinal fibers and tectal cells in frogs and goldfish. The model distinguishes two aspects of retinotectal connectivity: (1) the contact adhesion between retinal fibers and tectal cells as mediated by fixed chemospecific markers and (2) the formation of modifiable synapses between ...
متن کاملAdhesive recognition and retinotectal specificity.
An assay has been developed to test the hypothesis that neurons from a limited area of the retina will adhere preferentially to that part of the optic tectum near their normal synaptic termini. The method measures the adherence of (32)P-labeled cell bodies from either the dorsal or ventral half of the neural retina of chick embryos to dorsal and ventral tectal halves. When a labeled, single-cel...
متن کاملSpecificity and Plasticity of Thalamocortical Connections in Sema6A Mutant Mice
The establishment of connectivity between specific thalamic nuclei and cortical areas involves a dynamic interplay between the guidance of thalamocortical axons and the elaboration of cortical areas in response to appropriate innervation. We show here that Sema6A mutants provide a unique model to test current ideas on the interactions between subcortical and cortical guidance mechanisms and cor...
متن کاملEmergence of Input Specificity of LTP during Development of Retinotectal Connections In Vivo
Input specificity of activity-induced synaptic modification was examined in the developing Xenopus retinotectal connections. Early in development, long-term potentiation (LTP) induced by theta burst stimulation (TBS) at one retinal input spreads to other unstimulated converging inputs on the same tectal neuron. As the animal develops, LTP induced by the same TBS becomes input specific, a change...
متن کاملthe innovation of a statistical model to estimate dependable rainfall (dr) and develop it for determination and classification of drought and wet years of iran
آب حاصل از بارش منبع تأمین نیازهای بی شمار جانداران به ویژه انسان است و هرگونه کاهش در کم و کیف آن مستقیماً حیات موجودات زنده را تحت تأثیر منفی قرار می دهد. نوسان سال به سال بارش از ویژگی های اساسی و بسیار مهم بارش های سالانه ایران محسوب می شود که آثار زیان بار آن در تمام عرصه های اقتصادی، اجتماعی و حتی سیاسی- امنیتی به نحوی منعکس می شود. چون میزان آب ناشی از بارش یکی از مولفه های اصلی برنامه ...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1981
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.01-12-01369.1981